“To review the incidence, trends, risk factors, indication


“To review the incidence, trends, risk factors, indications for, and complications associated with cesarean hysterectomy (CH) in our institution.

Retrospective study of 158 women who had CH at the Detroit Medical Center during a 17 period.

During the study

period, 158 of 202,356 deliveries were CH, giving an overall incidence of 0.78 per 1,000 deliveries. Of the 158 cases, 14 were elective while 144 were emergently performed due to complications encountered at cesarean section. Analysis of the eligible 144 cases showed that the commonest risk factors were previous cesarean delivery (76%) and placenta previa (35%). Abnormal placenta adherence was the indication for CH in 50.7%, followed by uterine atony in 34.7% and uterine rupture selleckchem in 16.7% of the cases. Febrile morbidity (44.4%) and disseminated intravascular coagulopathy (22.9%) were the most common postoperative complications. Most complications occurred in patients with parity greater than two. Compared to the last decade, CH performed more recently were less likely to be complicated by bowel injury or disseminated intravascular coagulopathy.

Morbidly adherent placenta has replaced uterine atony as the leading indication for emergent CH in our institution. High parity remains a risk factor for complications; however, we recorded a reduction in bowel injury and disseminated intravascular

coagulopathy in recent years.”
“In this article, a series of poly(ether ester) bioelastomers, Integrin inhibitor poly(PEG-co-CA)s (PECs), were synthesized by the melt polycondensation of citric acid (CA) and poly(ethylene glycol) (PEG) with molecular weights of 150, 200, 300, and 400. The measurements of the mechanical properties of the PEC series testified that these polymers were elastomers with a low hardness and high elongation, and the hydrolytic degradation of polymer films in a buffer of pH 7.4 at 37 degrees C showed that the PECs had excellent degradability. The molecular

weight of PEG had a strong influence on the degradation rates, water absorption rates, and mechanical performance of the PECs. The materials are expected to be useful for pressure hemostasis implementation in Entinostat nmr lacuna and other biomedical applications. (C) 2010 Wiley Periodicals, Inc. J Appl Polym Sci 118: 2442-2447, 2010″
“Background: Intercellular adhesion molecule-1 (ICAM-1) is a cytoadhesion molecule implicated in the pathogenesis of Plasmodium falciparum malaria. Elevated levels of soluble ICAM-1 (sICAM-1) have previously been reported with increased malaria disease severity. However, studies have not yet examined both sICAM-1 concentrations and monocyte ICAM-1 expression in the same cohort of patients. To better understand the relationship of soluble and cellular ICAM-1 measurements in malaria, both monocyte ICAM-1 expression and sICAM-1 concentration were measured in children with P. falciparum infection exhibiting a spectrum of clinical severity.

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